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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
18.48
Human Site:
T612
Identified Species:
29.05
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
T612
K
E
K
K
Q
I
T
T
S
P
I
T
V
R
K
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
T612
K
E
K
K
Q
I
T
T
S
P
I
T
V
R
K
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
T364
A
P
A
P
A
P
A
T
E
G
L
D
A
K
E
Dog
Lupus familis
XP_534537
1097
121903
R599
N
S
R
D
E
E
K
R
E
S
R
I
K
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
T611
K
E
K
K
Q
I
T
T
S
P
I
T
V
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S603
E
K
K
Q
I
T
T
S
P
V
P
V
R
K
N
Chicken
Gallus gallus
XP_419666
1136
127431
T618
K
E
K
K
Q
I
T
T
S
P
V
P
V
R
K
Frog
Xenopus laevis
NP_001087838
1118
125984
K607
P
V
P
V
R
K
N
K
R
D
E
E
R
R
E
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
M598
L
K
N
H
Q
Q
R
M
R
R
K
K
Q
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
G601
N
T
G
A
N
S
S
G
G
S
N
G
S
T
G
Honey Bee
Apis mellifera
XP_395146
1137
124999
I648
K
I
K
H
Q
S
P
I
P
E
R
K
H
M
S
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
K31
S
I
E
S
Y
Y
S
K
R
V
T
Q
C
A
E
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
S688
L
E
K
S
R
I
E
S
P
V
P
E
R
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
L311
R
N
E
R
R
V
E
L
E
T
E
L
T
S
H
Red Bread Mold
Neurospora crassa
P38679
598
67999
A153
Q
K
K
C
S
Q
L
A
S
D
F
F
K
D
S
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
0
N.A.
100
N.A.
N.A.
13.3
86.6
6.6
6.6
N.A.
0
20
0
26.6
P-Site Similarity:
100
100
26.6
13.3
N.A.
100
N.A.
N.A.
46.6
93.3
20
20
N.A.
6.6
20
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
7
0
7
7
0
0
0
0
7
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
14
0
7
0
7
0
% D
% Glu:
7
34
14
0
7
7
14
0
20
7
14
14
0
0
27
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
7
7
0
7
0
0
7
% G
% His:
0
0
0
14
0
0
0
0
0
0
0
0
7
0
7
% H
% Ile:
0
14
0
0
7
34
0
7
0
0
20
7
0
0
0
% I
% Lys:
34
20
54
27
0
7
7
14
0
0
7
14
14
14
27
% K
% Leu:
14
0
0
0
0
0
7
7
0
0
7
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% M
% Asn:
14
7
7
0
7
0
7
0
0
0
7
0
0
0
14
% N
% Pro:
7
7
7
7
0
7
7
0
20
27
14
7
0
0
0
% P
% Gln:
7
0
0
7
40
14
0
0
0
0
0
7
7
0
0
% Q
% Arg:
7
0
7
7
20
0
7
7
20
7
14
0
20
40
0
% R
% Ser:
7
7
0
14
7
14
14
14
34
14
0
0
7
14
14
% S
% Thr:
0
7
0
0
0
7
34
34
0
7
7
20
7
7
0
% T
% Val:
0
7
0
7
0
7
0
0
0
20
7
7
27
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _